The manufacturing industry experiences technology and business disruption that will directly affect capabilities on productivity and scalability, as well as market and ecosystem requirements. Digitalization through intelligent systems and digital product life cycle management (PLM), as well as industrial Internet of Things (IoT), are generating data insights that are significant in creating manufacturing value chains. The emerging data exchanges will require edge computing requirements, especially in the automotive industry for connected platforms. Embedded artificial intelligence in automation will enhance digital business outcomes, while the benefits of blockchain for transparency are still emerging. Digital transformation also requires a sustainable strategy in organizational change management capabilities, leading to digital culture.