What are the best practices for delivering application load balanced hosting services with effective backup plan at multiple locations?

My suggestions is to draft your understanding of these 3 key points for your application.
RCO, RPO and RTO - Once you know what is best for your business users then you can easily work with your infrastructure team to draft the backup strategies for cloud or on premise application hosting. There are multiple solutions available based on your need, technology availability, tools management.  

Ensuring robust application load balancing across multiple locations is paramount in today's distributed landscape. Best practices include implementing redundant load balancers, leveraging geo-distributed data centers, and regularly testing failover mechanisms. A well-crafted backup plan ensures seamless continuity even in unexpected scenarios, maintaining service availability and user satisfaction.